Publications

Mechanistic Simulation Identifies Predictive Dose-Dependent Biomarkers of Propofol Anesthesia
bioRxiv (preprint)
•
2026

Authors: Pathak, Brincat, Xiong, Organtzidis, Protter, Du, Strey, Mujica-Parodi, Miller, Granger. Keywords: propofol, anesthesia, anesthetic, GABA-A, receptor, neuropharmacology, pharmacological modulation, mechanistic model, multiscale, simulation, model, modeling, thalamocortical, core-matrix, thalamus, cortex, spiking, field potentials, coherence, auditory oddball, sensory processing, macaque, functional connectivity, humans, dose-dependent biomarker, biomarker, inter-stimulus cortical activity, predictive neuropharmacology.

Read More
Mechanistic Corticostriatal Circuit Model Predicts Learning-Dependent fMRI Dynamics and Individual Reward Bias in Humans
bioRxiv (preprint)
•
2026

Authors: Carter, Kuang, Chesebro, Jumana, Burke, Pathak, Ratai, Miller, Granger, Mujica-Parodi. Keywords: corticostriatal, circuit model, biophysical model, mechanistic, computational model, model, modeling, local field potential, LFP, fMRI, functional magnetic resonance imaging, balloon model, hemodynamic, BOLD, prefrontal-striatal coherence, prefrontal cortex, striatum, learning, category-selective representations, reward bias, individual differences, single-subject, amplitude of low-frequency fluctuations, ALFF, dopamine, dopaminergic, biomarkers.

Read More
The Role of Structural Connectivity on Brain Function Through a Markov Model of Signal Transmission
PLOS ONE
•
2025

Authors: Razban, Banerjee, Mujica-Parodi, Bahar. Keywords: structural connectivity, functional connectivity, structure-function, Markov model, Markovian process, signal transmission, random walk, commute time, diffusion MRI, dMRI, white matter tracts, fMRI, functional MRI, functional magnetic resonance imaging, UK Biobank, HCP, Human Connectome Project, communicability, search information, polysynaptic, indirect connectivity.

Read More
Higher Fasting Brain Glucose is Associated with Lower Gray Matter Volume in Healthy Adults
Journal of Cerebral Blood Flow and Metabolism
•
2026

Authors: van Nieuwenhuizen, Antal, Hone-Blanchet, Lithen, McMahon, Jenkins, Ratai, Mujica-Parodi. Keywords: magnetic resonance imaging, structural MRI, functional MRI, fMRI, magnetic resonance spectroscopy, MRS, glucose, atrophy, aging, fasting, metabolic, metabolism, diabetes, brain.

Read More
Integration of Metabolic Flux Equations for Neurotransmitter Cycling Predicts Glutamate and GABA Dynamics in Response to Ketone Body Administration
Neurochemical Research (in press)
•
2026

Authors: Antal, Mujica-Parodi, Strey, Ratai, Mangia, Rothman. Keywords: model, modeling, glucose, ketones, ketosis, Neuroblox, magnetic resonance spectroscopy, MRS, metabolic, metabolism, flux equations, glycolysis, mitochondria, energy.

Read More
Scientific Machine Learning of Chaotic Systems Learns Reduced-Order Equations for Neural Populations
PRX Intelligence (in press)
•
2026

Authors: Chesebro, Hofmann, Dixit, Miller, Granger, Edelman, Rackauckas, Mujica-Parodi, Strey. Keywords: scientific machine learning, SciML, PEM-UDE, prediction-error method, universal differential equations, UDE, chaotic systems, chaos, governing equations, reduced-order equations, reduced-order closure, Rossler attractor, electrical circuit, noise, neural populations, neural mass model, Izhikevich neurons, sparse connectivity, connection density, oscillation frequency, synchrony, intracranial recordings, multi-scale, multiscale, model, modeling.

Read More
Spatially Convergent Functional MRI Signatures of Diabetes and Male Sex Identify Genetic Vulnerabilities to Accelerated Brain Ageing
Brain Communications
•
2026

Authors: Chesebro, Rohm, Antal, Weistuch, Strey, Ratai, Jones, Mujica-Parodi. Keywords: network, fMRI, functional magnetic resonance imaging, MRI, genetics, genome, diabetes, male, female, age, aging, dementia, metabolic, metabolism.

Read More
Mechanistic Signatures of Comorbid PTSD with Cognitive Impairment Implicate Cortisol-Induced Neural Toxicity
Neuropsychopharmacology
•
2026

Authors: Kuang, Chesebro, Strey, Clouston, Luft, Mujica-Parodi. Keywords: PTSD, post-traumatic stress disorder, cognitive impairment, cognitive decline, World Trade Center, 9/11, rescue and recovery, trauma, stress, cortisol, neurotoxicity, cortisol-induced neurotoxicity, p53, machine learning, fMRI, functional magnetic resonance imaging, mRNA expression, gene expression, transcriptomic, ZNF48, TOMM40, GRIN1, structural equation modeling, SEM, biomarkers.

Read More
Opportunities and Challenges in Precision Neurotherapeutics
Annual Review of Biomedical Engineering
•
2026

Authors: Mujica-Parodi, Öngür, Ongur, Richardson. Keywords: precision neurotherapeutics, precision medicine, personalized, individualized, neurological, neurodegenerative, psychiatric disorders, drug discovery, fragment-based drug discovery, pharmacokinetic modeling, quantitative systems pharmacology, QSP, neuromodulation, closed-loop, biomarkers, neuroimaging, pharmacogenomics, digital health, single-subject parameter estimation, signal-to-noise ratio, regulatory, FDA, in silico, artificial intelligence, AI, computational modeling, mental health, review, central nervous system, medical device, neurotransmitter, pharmaceutical.

Read More
Biomimetic Model of Corticostriatal Micro-Assemblies Discovers a Neural Code
Nature Communications
•
2025

Authors: Pathak, Brincat, Organtzidis, Strey, Senneff, Antzoulatos, Mujica-Parodi, Miller, Granger. Keywords: Neuroblox, model, modeling, multiscale, biomimetic computational primitive, BCP, category learning, cognition, neuron, incongruent, macaque.

Read More
Shared and Distinct Alterations in Brain Structure of Youth with Internalizing or Externalizing Disorders: Findings from the ENIGMA Antisocial Behavior, ADHD, MDD, and Anxiety Working Groups
Biological Psychiatry
•
2025

Authors: Townend, Staginnus, Gao, Alexander, Arolt, Banaschewski, Beesdo-Baum, Bellgrove, Benegal, Blair, Blanco-Hinojo, Boeken, Böhnlein, Bohnlein, Bölte, Bolte, Bonnekoh, Brandeis, Bressan, Breuer, Bruin, Buitelaar, Burkhouse, Calkins, Cano, Cardoner, Chen, Chen, Coghill, Colins, Connolly, Craig, Cullen, Dannlowski, Davey, Dietrich, Dong, Freitag, Frodl, Goossens, Grotegerd, Gur, Gur, Haavik, Hagan, Hahn, Hamm, Harrison, Hartman, Herrmann, Ho, Hoekstra, Holla, Ibrahim, Jackowski, Jamalabadi, Jiang, Kircher, Konrad, Kraus, Kuntsi, Langhammer, Lazaro, Leehr, Lueken, Ma, MacMaster, Manfro, Martinelli, Meinert, Meinert, Michałowski, Michalowski, Ming, Moeck, Muehlhan, Mujica-Parodi, Mwangi, Neufeld, Nigg, O'Gorman Tuura, Oh, Oosterlaan, Paloyelis, Pan, Passamonti, Peñate, Penate, Phan, Plessen, Pujol, Remnélius, Remnelius, Rivero, Rubia, Salas, Salum, Satterthwaite, Schienle, Schrammen, Schruers, Schumann, Sethi, Silk, Skokauskas, Smoller, Soares, Sørensen, Sorensen, Stadler, Stevens, Straube, Straube, Ströhle, Strohle, Sudre, Sukhodolsky, Sully, Sun, Sylvester, Toschi, van der Werff, Vance, Vermeiren, Wabnegger, Wang, Wendt, Whittle, Wiemer, Winkler, Wittchen, Wu, Wu, Yang, Yang, Yao, Zhang, Zhou, Zugman, Zunta-Soares, Zwanzger, Thomopoulos, Jahanshad, Thompson, Hilbert, Baskin-Sommers, Cecil, Aghajani, Pine, van der Wee, Stein, Groenewold, Bas-Hoogendam, Han, Pozzi, Schmaal, Franke, Hoogman, Walton, De Brito, Fairchild, ENIGMA Antisocial Behavior, Anxiety, ADHD, and MDD Working Groups. Keywords: ENIGMA, consortium, mega-analysis, structural MRI, magnetic resonance imaging, brain structure, cortical thickness, surface area, subcortical volume, youth, children, adolescents, internalizing, externalizing, transdiagnostic, anxiety, depression, MDD, ADHD, conduct disorder, antisocial behavior, amygdala, insula, psychiatry.

Read More
Brain and Body Energy Metabolism and Potential for Treatment of Psychiatric Disorders
Nature Mental Health
•
2025

Authors: Andreazza, Barros, Behnke, Ben-Shachar, Berretta, Chouinard, Do, Edwin Thanarajah, Ehrenreich, Falkai, Ford, Freyberg, Gilbert-Jaramillo, Glausier, Goyal, Hahn, Herculano-Houzel, Hofmann, Kolassa, Mack, Mavioglu, McCullumsmith, Milaneschi, Molina, Mujica-Parodi, Öngür, Ongur, Paulus, Peleg-Raibstein, Perry, Picard, Pillinger, Rae, Rothman, Sarnyai, Steiner, Upthegrove, Vernon, Wall, Weistuch. Keywords: psychiatry, metabolism, metabolic, ketosis, ketogenic.

Read More
Ketosis Elevates Antioxidants and Markers of Energy Metabolism: A 1H MR Spectroscopy Study
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
•
2025

Authors: van Nieuwenhuizen, Antal, Hone-Blanchet, Lithen, McMahon, Nikolaidou, Kuang, Clarke, Jenkins, Rothman, Mujica-Parodi, Ratai. Keywords: ketosis, ketones, ketone monoester, glucose, metabolism, metabolic, bioenergetics, antioxidants, energy markers, creatine, GABA, glutamate, glutamine, magnetic resonance spectroscopy, MRS, 1H-MRS, 7T, ultra high field, resting-state fMRI, functional magnetic resonance imaging, functional connectivity, posterior cingulate, lifespan.

Read More
Increasing Spectral DCM Flexibility and Speed by Leveraging Julia's ModelingToolkit and Automated Differentiation
Imaging Neuroscience
•
2025

Authors: Hofmann, Chesebro, Rackauckas, Mujica-Parodi, Friston, Edelman, Strey. Keywords: spectral DCM, dynamic causal modeling, DCM, Julia, ModelingToolkit, Neuroblox, automatic differentiation, parameter estimation, model fitting, inverse problem, SPM, fMRI, functional magnetic resonance imaging, LFP, neuroimaging, circuit, model, modeling, software, 7T.

Read More
Brain Aging Shows Nonlinear Transitions, Suggesting a Midlife "Critical Window" for Metabolic Intervention
Proceedings of the National Academy of Sciences of the USA
•
2025

Authors: Antal, van Nieuwenhuizen, Chesebro, Strey, Jones, Clarke, Weistuch, Ratai, Dill, Mujica-Parodi. Keywords: brain aging, aging, age, midlife, critical window, nonlinear, brain networks, network destabilization, fMRI, functional MRI, functional magnetic resonance imaging, glucose, glucose homeostasis, insulin, GLUT4, APOE, MCT2, ketones, ketone transporter, gene expression, metabolic, metabolism, metabolic intervention, neurodegenerative diseases, biomarkers, vascular, inflammatory, neuron.

Read More
Challenges and Frontiers in Computational Metabolic Psychiatry
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
•
2025

Authors: Chesebro, Antal, Weistuch, Mujica-Parodi. Keywords: computational metabolic psychiatry, metabolic psychiatry, psychiatry, computational models, computational, model, modeling, multiscale, circuit, dysregulation, feedback, tricarboxylic acid cycle, TCA cycle, ion channel, neural microassembly, macrocircuit, neural, endocrine, immune, vascular, in vitro, in vivo, personalized diagnostics, allostasis, homeostasis, metabolic, metabolism.

Read More
Parameter Estimation from an Ornstein-Uhlenbeck Process with Measurement Noise
Physical Review E
•
2024

Authors: Carter, Mujica-Parodi, Strey. Keywords: Ornstein-Uhlenbeck process, parameter estimation, measurement noise, noise, thermal noise, multiplicative noise, white noise, signal separation, Hamilton Monte Carlo, Hamiltonian Monte Carlo, HMC, algorithm, sampling rate.

Read More
Achieving Occam's Razor: Deep Learning for Optimal Model Reduction
PLOS Computational Biology
•
2024

Authors: Antal, Chesebro, Strey, Mujica-Parodi, Weistuch. Keywords: Occam's razor, FixFit, deep learning, neural network, bottleneck layer, model reduction, redundancy, model parameters, parameter fitting, latent parameters, composite parameters, Kepler orbit, blood glucose regulation, glucose, multi-scale brain model, multiscale, model, modeling.

Read More
Brain Signaling Becomes Less Integrated and More Segregated with Age
Network Neuroscience
•
2024

Authors: Razban, Antal, Dill, Mujica-Parodi. Keywords: integration, segregation, integration-segregation, aging, age, Ising model, statistical physics, order, disorder, fMRI, functional MRI, functional magnetic resonance imaging, structural MRI, diffusion MRI, dMRI, brain dynamics, connection strength.

Read More
D-β-Hydroxybutyrate Stabilizes Hippocampal CA3-CA1 Circuit During Acute Insulin Resistance
PNAS Nexus
•
2024

Authors: Kula, Antal, Weistuch, Gackière, Gackiere, Barre, Velado, Hubbard, Kukley, Mujica-Parodi, Smith. Keywords: D-β-hydroxybutyrate, D-βHb, beta-hydroxybutyrate, BHB, ketone bodies, ketones, insulin resistance, acute insulin resistance, GLUT4, glucose, glycolysis, mitochondrial respiration, metabolism, hypometabolic, hippocampus, CA3-CA1, synaptic activity, long-term potentiation, LTP, axonal conduction, synchronization, action potential, neurons, mouse.

Read More
Ketosis Regulates K+ Ion Channels, Strengthening Brain-Wide Signaling Disrupted by Age
Imaging Neuroscience
•
2024

Authors: van Nieuwenhuizen, Chesebro, Polizu, Clarke, Strey, Weistuch, Mujica-Parodi. Keywords: ketosis, ketones, ketone ester, glucose, metabolism, metabolic, aging, age, potassium, K+, ion channels, ion gradients, synchrony, desynchronization, brain networks, network stability, resting-state fMRI, functional magnetic resonance imaging, EEG, electroencephalography, multiscale modeling, neural mass model, model, modeling.

Read More
Quantifying Individual Variability in Neural Control Circuit Regulation Using Single-Subject fMRI
Computational Brain & Behavior
•
2023

Authors: Kumar, Strey, Mujica-Parodi. Keywords: control systems, control circuit, control systems engineering, controllability, regulation, dysregulation, system identification, perturbation, stress, single-subject, individual variability, precision, neurodiagnostics, fMRI, functional magnetic resonance imaging, generative model, computational model, modeling, psychiatry, circuit.

Read More
Early Path Dominance as a Principle for Neurodevelopment
Proceedings of the National Academy of Sciences of the USA
•
2023

Authors: Razban, Pachter, Dill, Mujica-Parodi. Keywords: neurodevelopment, development, connectomics, connectome, diffusion MRI, dMRI, white matter, tracts, network neuroscience, percolation theory, targeted attack, giant cluster, statistical mechanics, UK Biobank, ABCD, Adolescent Brain Cognitive Development, Developing Human Connectome Project, aging.

Read More
Ion Gradient-Driven Bifurcations of a Multi-Scale Neuronal Model
Chaos, Solitons & Fractals
•
2023

Authors: Chesebro, Mujica-Parodi, Weistuch. Keywords: ion gradients, ion pumps, bifurcation, bifurcation theory, neural mass model, Larter-Breakspear, Morris-Lecar, conductance-based model, multiscale, model, modeling, metabolism, metabolic, energy, aging, sodium, calcium, potassium, synchrony, coherence, nonlinear dynamics.

Read More
Acute Administration of Ketone Beta-Hydroxybutyrate Downregulates 7T Proton Magnetic Resonance Spectroscopy-Derived Levels of Anterior and Posterior Cingulate GABA and Glutamate in Healthy Adults
Neuropsychopharmacology
•
2023

Authors: Hone-Blanchet, Antal, McMahon, Lithen, Smith, Stufflebeam, Yen, Lin, Jenkins, Mujica-Parodi, Ratai. Keywords: ketones, beta-hydroxybutyrate, D-βHB, BHB, ketone monoester, glucose, metabolism, metabolic, fasting, GABA, glutamate, magnetic resonance spectroscopy, MRS, 7T, ultra high field, anterior cingulate, posterior cingulate, aging, age, neurotransmitters.

Read More
Type 2 Diabetes Mellitus Accelerates Brain Aging and Cognitive Decline: Complementary Findings from UK Biobank and Meta-Analyses
eLife
•
2022

Authors: Antal, McMahon, Sultan, Lithen, Wexler, Dickerson, Ratai, Mujica-Parodi. Keywords: type 2 diabetes, T2DM, diabetes, aging, brain aging, cognitive decline, cognition, executive function, processing speed, neurodegeneration, gray matter atrophy, ventral striatum, metformin, UK Biobank, meta-analysis, MRI, functional MRI, fMRI, neuroimaging, metabolism, neurometabolic, biomarker, epidemiology.

Read More
Detection of COVID-19 Using Multimodal Data from a Wearable Device: Results from the First TemPredict Study
Scientific Reports
•
2022

Authors: Mason, Hecht, Davis, Natale, Hartogensis, Damaso, Claypool, Dilchert, Dasgupta, Purawat, Viswanath, Klein, Chowdhary, Fisher, Anglo, Puldon, Veasna, Prather, Pandya, Fox, Busch, Giordano, Mercado, Song, Jaimes, Baum, Telfer, Philipson, Collins, Rao, Wang, Bandi, Choe, Epel, Epstein, Krasnoff, Lee, Lee, Lopez, Mehta, Melville, Moon, Mujica-Parodi, Noel, Orosco, Rideout, Robishaw, Rodriguez, Shah, Siegal, Gupta, Altintas, Smarr. Keywords: COVID-19, SARS-CoV-2, wearable device, Oura Ring, TemPredict, temperature, physiological data, early detection, machine learning, classification, algorithm.

Read More
ENIGMA-Anxiety Working Group: Rationale for and Organization of Large-Scale Neuroimaging Studies of Anxiety Disorders
Human Brain Mapping
•
2022

Authors: Bas-Hoogendam, Groenewold, Aghajani, Freitag, Harrewijn, Hilbert, Jahanshad, Thomopoulos, Thompson, Veltman, Winkler, Lueken, Pine, van der Wee, Stein, ENIGMA-Anxiety Working Group. Keywords: ENIGMA, ENIGMA-Anxiety, consortium, working group, anxiety, anxiety disorders, generalized anxiety disorder, GAD, panic disorder, social anxiety disorder, specific phobia, neuroimaging, magnetic resonance imaging, MRI, genetics, amygdala, limbic system, prefrontal cortex, global mental health.

Read More
NeuroPredictome: A data-driven predictome linking neuroimaging to phenotype
2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
•
2021

Authors: Sultan, Mujica-Parodi, Skiena. Keywords: NeuroPredictome, predictome, UK Biobank, phenotype, neuroimaging, fMRI, functional magnetic resonance imaging, prediction, data-driven, brain mapping, decoding, meta-analysis, public resource.

Read More
Development of an MRI-Compatible Nasal Drug Delivery Method for Probing Nicotine Addiction Dynamics
Pharmaceutics
•
2021

Authors: Kumar, Mujica-Parodi, Wenke, Amgalan, Lithen, Govindarajan, Makaryus, Benveniste, Strey. Keywords: nicotine, addiction, cigarette, substance abuse, craving, reward, control system, control circuit, nasal drug delivery, nebulizer, MRI-compatible device, pharmacokinetics, single-subject, MRI, dysregulation, neuromodulation.

Read More
Metabolism Modulates Network Synchrony in the Aging Brain
Proceedings of the National Academy of Sciences of the USA
•
2021

Authors: Weistuch, Mujica-Parodi, Razban, Antal, van Nieuwenhuizen, Amgalan, Dill. Keywords: aging, age, metabolism, metabolic, neurometabolism, hypometabolism, synchrony, network synchrony, criticality, critical point, Ising model, statistical physics, generative model, fMRI, functional magnetic resonance imaging, functional connectivity, brain networks.

Read More
The Refractory Period Matters: Unifying Mechanisms of Macroscopic Brain Waves
Neural Computation
•
2021

Authors: Weistuch, Mujica-Parodi, Dill. Keywords: refractory period, brain waves, oscillations, maximum caliber, mean field, neural populations, neurons, model, modeling, dynamical inference.

Read More
Machine Learning Predicts Outcomes of Phase III Clinical Trials for Prostate Cancer
Algorithms
•
2021

Authors: Beacher, Mujica-Parodi, Gupta, Ancora. Keywords: machine learning, ML, clinical trials, Phase III, prostate cancer, cancer, oncology, bicalutamide, outcome prediction, precision medicine, drug development.

Read More
Cortical and Subcortical Brain Structure in Generalized Anxiety Disorder: Findings from 28 Research Sites in the ENIGMA-Anxiety Working Group
Translational Psychiatry
•
2021

Authors: Harrewijn, Cardinale, Groenewold, Bas-Hoogendam, Aghajani, Hilbert, Cardoner, Porta-Casteràs, Porta-Casteras, Gosnell, Salas, Jackowski, Pan, Salum, Blair, Blair, Hammoud, Milad, Burkhouse, Phan, Schroeder, Strawn, Beesdo-Baum, Jahanshad, Thomopoulos, Buckner, Nielsen, Smoller, Soares, Mwangi, Wu, Zunta-Soares, Assaf, Diefenbach, Brambilla, Maggioni, Hofmann, Straube, Andreescu, Berta, Tamburo, Price, Manfro, Agosta, Canu, Cividini, Filippi, Kostić, Kostic, Munjiza Jovanovic, Alberton, Benson, Freitag, Filippi, Gold, Leibenluft, Ringlein, Werwath, Zwiebel, Zugman, Grabe, Van der Auwera, Wittfeld, Völzke, Volzke, Bülow, Bulow, Balderston, Ernst, Grillon, Mujica-Parodi, van Nieuwenhuizen, Critchley, Makovac, Mancini, Meeten, Ottaviani, Ball, Fonzo, Paulus, Stein, Gur, Gur, Kaczkurkin, Larsen, Satterthwaite, Harper, Myers, Perino, Sylvester, Yu, Lueken, Veltman, Thompson, Stein, Van der Wee, Winkler, Pine. Keywords: ENIGMA, ENIGMA-Anxiety, consortium, mega-analysis, generalized anxiety disorder, GAD, anxiety, brain structure, structural MRI, magnetic resonance imaging, cortical thickness, surface area, subcortical volume, FreeSurfer, ventral diencephalon, sex differences, children, adults.

Read More
Unique Scales Preserve Self-Similar Integrate-and-Fire Functionality of Neuronal Clusters
Scientific Reports
•
2021

Authors: Amgalan, Taylor, Mujica-Parodi, Siegelmann. Keywords: neuronal clusters, integrate-and-fire, self-similar, fractal, scales, coarse-graining, hierarchical clustering, brain networks, network, fMRI, computational simulation, model, modeling, multiscale, artificial intelligence, evolution, development.

Read More
"Ground-Truth" Resting-State Signal Provides Data-Driven Estimation and Correction for Scanner Distortion of fMRI Timeseries Dynamics
NeuroImage
•
2021

Authors: Kumar, Tan, Kriegstein, Lithen, Polimeni, Mujica-Parodi, Strey. Keywords: functional magnetic resonance imaging, fMRI, 7T, ultra high field, phantom, calibration, precision medicine, n=1, BrainDancer, dynamic, Dynamic fidelity, Dynamic phantom, Marchenko-Pastur distribution, Multi-site, Scanner instability.

Read More
Fast Spatial Autocorrelation
Proceedings of the IEEE International Conference on Data Mining (ICDM)
•
2020

Authors: Amgalan, Mujica-Parodi, Skiena. Keywords: spatial autocorrelation, Moran's I, Geary's C, algorithm, linear-time, statistics, clustering.

Read More
Inferring a Network from Dynamical Signals at Its Nodes
PLOS Computational Biology
•
2020

Authors: Weistuch, Agozzino, Mujica-Parodi, Dill. Keywords: network inference, inverse problem, network topology, maximum caliber, time-dependent signals, dynamical signals, neurons, neural network, genetic toggle switch, model, modeling.

Read More
Mega-Analysis Methods in ENIGMA: The Experience of the Generalized Anxiety Disorder Working Group
Human Brain Mapping
•
2022

Authors: Zugman, Harrewijn, Cardinale, Zwiebel, Freitag, Werwath, Bas-Hoogendam, Groenewold, Aghajani, Hilbert, Cardoner, Porta-Casteràs, Porta-Casteras, Gosnell, Salas, Blair, Blair, Hammoud, Milad, Burkhouse, Phan, Schroeder, Strawn, Beesdo-Baum, Thomopoulos, Grabe, Van der Auwera, Wittfeld, Nielsen, Buckner, Smoller, Mwangi, Soares, Wu, Zunta-Soares, Jackowski, Pan, Salum, Assaf, Diefenbach, Brambilla, Maggioni, Hofmann, Straube, Andreescu, Berta, Tamburo, Price, Manfro, Critchley, Makovac, Mancini, Meeten, Ottaviani, Agosta, Canu, Cividini, Filippi, Kostić, Kostic, Munjiza, Filippi, Leibenluft, Alberton, Balderston, Ernst, Grillon, Mujica-Parodi, van Nieuwenhuizen, Fonzo, Paulus, Stein, Gur, Gur, Kaczkurkin, Larsen, Satterthwaite, Harper, Myers, Perino, Yu, Sylvester, Veltman, Lueken, Van der Wee, Stein, Jahanshad, Thompson, Pine, Winkler. Keywords: ENIGMA, ENIGMA-Anxiety, consortium, mega-analysis, meta-analysis, generalized anxiety disorder, GAD, anxiety, data sharing, methods, quality control, neuroimaging, brain structure, structural MRI, genetics, pipeline.

Read More
Making Sense of Computational Psychiatry
International Journal of Neuropsychopharmacology
•
2020

Authors: Mujica-Parodi, Strey. Keywords: computational psychiatry, psychiatry, model, modeling, computational model, dynamical systems, generative models, system identification, control systems, circuit, machine learning, RDoC, fMRI, neuroimaging, statistics, hypothesis-driven, data-driven.

Read More
Diet Modulates Brain Network Stability, a Biomarker for Brain Aging, in Young Adults
Proceedings of the National Academy of Sciences of the USA
•
2020

Authors: Mujica-Parodi, Amgalan, Sultan, Antal, Sun, Skiena, Lithen, Adra, Ratai, Weistuch, Govindarajan, Strey, Dill, Stufflebeam, Veech, Clarke. Keywords: diet, ketogenic diet, ketones, ketosis, ketone ester, beta-hydroxybutyrate, glucose, fasting, insulin resistance, metabolism, metabolic, hypometabolism, brain network stability, network stability, biomarker, brain aging, aging, age, dementia, cognition, fMRI, functional magnetic resonance imaging, 7T, ultra high field, lifespan.

Read More
Oxytocin Attenuates Trust as a Subset of More General Reinforcement Learning in Males
NeuroImage
•
2018

Authors: Ide, Nedic, Wong, Strey, Lawson, Dickerson, Wald, La Camera, Mujica-Parodi. Keywords: oxytocin, trust, Iterative Trust Game, neuroeconomics, reinforcement learning, reward, prediction error, Bayesian modeling, social learning, feedback learning, males, fMRI, functional magnetic resonance imaging, 7T, ultra high field, orbitofrontal cortex, amygdala, habenula, reward circuit, connectivity.

Read More
From Anxious to Reckless: A Control Systems Approach Unifies Prefrontal-Limbic Regulation Across the Spectrum of Threat Detection
Frontiers in Neuroscience
•
2017

Authors: Mujica-Parodi, Cha, Gao. Keywords: control systems, control circuit, regulation, negative feedback, prefrontal-limbic, inferior frontal gyrus, IFG, ventromedial prefrontal cortex, vmPFC, amygdala, limbic, threat detection, fear, anxiety, sensation-seeking, reckless, addiction, chaotic dynamics, computational model, modeling, fMRI, neuroimaging, review.

Read More
Lost Emotion: Disrupted Brain-Based Tracking of Dynamic Affective Episodes in Anxiety and Depression
Psychiatry Research: Neuroimaging
•
2017

Authors: Carlson, Rubin, Mujica-Parodi. Keywords: emotion, affect, emotional numbing, anxiety, depression, generalized anxiety disorder, GAD, major depressive disorder, MDD, fMRI, functional magnetic resonance imaging, video, natural vision, default mode network, amygdala, dynamic.

Read More
Signal Fluctuation Sensitivity: An Improved Metric for Optimizing Detection of Resting-State fMRI Networks
Frontiers in Neuroscience
•
2016

Authors: DeDora, Nedic, Katti, Arnab, Wald, Takahashi, Van Dijk, Strey, Mujica-Parodi. Keywords: signal fluctuation sensitivity, SFS, temporal signal to noise ratio, tSNR, dynamic phantom, phantom, fidelity, scanner, artifact, quality metric, resting-state fMRI, functional magnetic resonance imaging, functional MRI, connectivity, default mode network, BOLD.

Read More
Clinically Anxious Individuals Show Disrupted Feedback Between Inferior Frontal Gyrus and Prefrontal-Limbic Control Circuit
Journal of Neuroscience
•
2016

Authors: Cha, DeDora, Nedic, Ide, Greenberg, Hajcak, Mujica-Parodi. Keywords: anxiety, clinical anxiety, generalized anxiety disorder, fear generalization, fear conditioning, inferior frontal gyrus, IFG, ventromedial prefrontal cortex, vmPFC, amygdala, prefrontal-limbic, control circuit, control systems, feedback, regulation, dysregulation, power spectrum scale invariance, PSSI, autocorrelation, entropy, dynamic causal modeling, DCM, diffusion MRI, tractography, fMRI, functional magnetic resonance imaging, connectivity, emotion regulation.

Read More
Power Spectrum Scale Invariance as a Neural Marker of Cocaine Misuse and Altered Cognitive Control
NeuroImage: Clinical
•
2016

Authors: Ide, Hu, Zhang, Mujica-Parodi, Li. Keywords: cocaine, cocaine addiction, cocaine dependence, addiction, stimulant, cocaine misuse, cognitive control, stop signal task, post-signal slowing, conflict monitoring, power spectrum scale invariance, PSSI, BOLD, fMRI, functional magnetic resonance imaging, MRI, prefrontal cortex, inferior frontal gyrus, frontoparietal, neural marker.

Read More
Abnormal Hippocampal Structure and Function in Anxiety and Depression
Hippocampus
•
2016

Authors: Cha, Greenberg, Song, Blair Simpson, Posner, Mujica-Parodi. Keywords: hippocampus, hippocampal subdivisions, CA1, microstructure, anxiety, depression, generalized anxiety disorder, GAD, MDD, comorbidity, threat processing, MRI, magnetic resonance imaging, diffusion MRI, structural MRI, functional MRI, fMRI, hippocampal segmentation, structural equation modeling, SEM.

Read More
Left Medial Orbitofrontal Cortex Volume Correlates with Skydive-Elicited Euphoric Experience
Brain Structure and Function
•
2016

Authors: Carlson, Cha, Fekete, Greenberg, Mujica-Parodi. Keywords: skydive, skydiving, euphoria, hedonia, positive affect, reward, medial orbitofrontal cortex, orbitofrontal cortex, medial prefrontal cortex, brain volume, structural MRI, magnetic resonance imaging, amygdala, hippocampus, corticolimbic.

Read More
Using Network Dynamic fMRI for Detection of Epileptogenic Foci
BMC Neurology
•
2015

Authors: Nedic, Stufflebeam, Rondinoni, Velasco, dos Santos, Leite, Gargaro, Mujica-Parodi, Ide. Keywords: epilepsy, temporal lobe epilepsy, epileptogenic foci, seizure, resting-state fMRI, functional magnetic resonance imaging, network dynamics, autocorrelation function, entropy, chaotic dynamics, functional connectivity, classification, memory, EEG, neurodiagnostics.

Read More
Acute Psychological Stress Induces Short-Term Variable Immune Response
Brain, Behavior, and Immunity
•
2015

Authors: Breen, Beliakova-Bethell, Mujica-Parodi, Carlson, Ensign, Woelk, Rana. Keywords: stress, acute psychological stress, skydive, skydiving, immune system, immune response, leukocytes, natural killer cells, gene expression, transcription, gene co-expression network, cortisol, catecholamines, endocrine, autonomic, sex differences, periphery.

Read More
Sulfobutyl Ether β-Cyclodextrin (Captisol®) and Methyl β-Cyclodextrin Enhance and Stabilize Fluorescence of Aqueous Indocyanine Green
Journal of Biomedical Materials Research Part B: Applied Biomaterials
•
2015

Authors: DeDora, Suhrland, Goenka, Mullick Chowdhury, Lalwani, Mujica-Parodi, Sitharaman. Keywords: indocyanine green, ICG, cyclodextrin, Captisol, fluorescence, near-infrared fluorophore, inclusion complex, vascular imaging, biomaterials, formulation.

Read More
Anticipation of High Arousal Aversive and Positive Movie Clips Engages Common and Distinct Neural Substrates
Social Cognitive and Affective Neuroscience
•
2015

Authors: Greenberg, Carlson, Rubin, Cha, Mujica-Parodi. Keywords: anticipation, anxious anticipation, uncertainty, valence, arousal, aversive, positive, reward, emotion, films, movie clips, fMRI, functional magnetic resonance imaging, anterior insula, anterior cingulate, nucleus accumbens, medial prefrontal cortex.

Read More
Facilitated Attentional Orienting and Delayed Disengagement to Conscious and Nonconscious Fearful Faces.
Nonverbal Behavior
•
2014

Authors: Carlson, Mujica-Parodi. Keywords: attention, attentional orienting, attentional disengagement, fearful faces, fear, threat, conscious, nonconscious, emotion.

Read More
Network Connectivity Modulates Power Spectrum Scale Invariance
NeuroImage
•
2014

Authors: Rădulescu, Radulescu, Mujica-Parodi. Keywords: power spectrum scale invariance, PSSI, scale-free, complexity, pink noise, 1/f, network connectivity, network density, excitatory, inhibitory, control system, prefrontal-limbic, meso-circuit, model, modeling, simulation, stochastic differential equations, neurovascular, hemodynamic, fMRI, functional magnetic resonance imaging, anxiety, biomarker, regulation.

Read More
The Fine Line Between 'Brave' and 'Reckless': Amygdala Reactivity and Regulation Predict Recognition of Risk
NeuroImage
•
2014

Authors: Mujica-Parodi, Carlson, Cha, Rubin. Keywords: sensation-seeking, risk, brave, reckless, skydive, skydiving, threat perception, fear, stress, cortisol, anxiety, resilience, amygdala, prefrontal-limbic, prefrontal cortex, inferior frontal gyrus, cortical thickness, regulation, complexity, chaos, fractal, power spectrum scale invariance, PSSI, fMRI, functional MRI, structural MRI, structural equation modeling.

Read More
Circuit-wide structural and functional measures predict ventromedial prefrontal cortex fear generalization: implications for generalized anxiety disorder
Journal of Neuroscience
•
2014

Authors: Cha, Greenberg, Carlson, Dedora, Hajcak, Mujica-Parodi. Keywords: generalized anxiety disorder, GAD, anxiety, fear generalization, fear conditioning, threat, safety, ventromedial prefrontal cortex, vmPFC, corticolimbic, cortical thickness, functional connectivity, structural connectivity, resting-state, tractography, diffusion MRI, structural MRI, fMRI, functional magnetic resonance imaging, BOLD.

Read More
Hyper-reactive human ventral tegmental area and aberrant mesocorticolimbic connectivity in overgeneralization of fear in generalized anxiety disorder
Journal of Neuroscience
•
2014

Authors: Cha, Carlson, Dedora, Greenberg, Proudfit, Mujica-Parodi. Keywords: generalized anxiety disorder, GAD, anxiety, fear generalization, overgeneralization of fear, fear conditioning, threat, ventral tegmental area, VTA, dopamine, dopaminergic, mesocorticolimbic, connectivity, fMRI, functional magnetic resonance imaging, trait anxiety.

Read More
Influence of the BDNF Genotype on Amygdalo-Prefrontal White Matter Microstructure is Linked to Nonconscious Attention Bias to Threat
Cerebral Cortex
•
2014

Authors: Carlson, Cha, Harmon-Jones, Mujica-Parodi, Hajcak. Keywords: BDNF, genotype, genetics, uncinate fasciculus, amygdala, prefrontal cortex, anterior cingulate, white matter, microstructure, diffusion tensor imaging, DTI, diffusion MRI, tractography, attention bias, threat, nonconscious, dot-probe, backward masking, anxiety.

Read More
Optimizing complexity measures for FMRI data: algorithm, artifact, and sensitivity
PLOS ONE
•
2013

Authors: Rubin, Fekete, Mujica-Parodi. Keywords: complexity, complexity measures, fractal, Hurst exponent, power spectrum, Higuchi fractal dimension, detrended fluctuation analysis, wavelet, algorithm, artifact, sensitivity, signal processing, time series, scanner, fMRI, functional magnetic resonance imaging, methods.

Read More
Human gender differences in the perception of conspecific alarm chemosensory cues
PLOS ONE
•
2013

Authors: Radulescu, Mujica-Parodi. Keywords: chemosensory, chemosignals, alarm pheromones, pheromones, stress sweat, sweat, olfaction, olfactory bulb, fear, stress, emotion, amygdala, gender differences, sex differences, fMRI, functional magnetic resonance imaging.

Read More
Ventromedial prefrontal cortex reactivity is altered in generalized anxiety disorder during fear generalization
Depression and Anxiety
•
2013

Authors: Greenberg, Carlson, Cha, Hajcak, Mujica-Parodi. Keywords: generalized anxiety disorder, GAD, anxiety, fear generalization, fear conditioning, fear inhibition, fear regulation, ventromedial prefrontal cortex, vmPFC, insula, anterior cingulate, amygdala, connectivity, psychophysiological interaction, fMRI.

Read More
Multiple kernel learning captures a systems-level functional connectivity biomarker signature in amyotrophic lateral sclerosis
PLOS ONE
•
2013

Authors: Fekete, Zach, Mujica-Parodi, Turner. Keywords: amyotrophic lateral sclerosis, ALS, neurodegeneration, neurodegenerative disorder, multiple kernel learning, machine learning, classification, pattern detection, biomarker, resting-state fMRI, functional magnetic resonance imaging, functional connectivity, motor network, complex network analysis, cerebellum, basal ganglia.

Read More
Combining classification with fMRI-derived complex network measures for potential neurodiagnostics
PLOS ONE
•
2013

Authors: Fekete, Wilf, Rubin, Edelman, Malach, Mujica-Parodi. Keywords: classification, machine learning, kernel learning, block diagonal optimization, BDopt, complex network analysis, graph theory, functional connectivity, resting-state fMRI, functional magnetic resonance imaging, schizophrenia, sleep, neurodiagnostics.

Read More
Small-world network properties in prefrontal cortex correlate with predictors of psychopathology risk in young children
NeuroImage
•
2014

Authors: Fekete, Beacher, Cha, Rubin, Mujica-Parodi. Keywords: near-infrared spectroscopy, NIRS, fNIRS, small-world network, complex network, prefrontal cortex, children, toddlers, development, developmental psychopathology, temperament, effortful control, anxiety, depression, ADHD, neurodiagnostics, naturalistic stimuli.

Read More
Functional and structural amygdala-anterior cingulate connectivity correlates with attentional bias to masked fearful faces
Cortex
•
2013

Authors: Carlson, Cha, Mujica-Parodi. Keywords: attention bias, attentional bias, threat, masked fearful faces, fear, nonconscious, dot-probe, backward masking, amygdala, anterior cingulate, uncinate fasciculus, functional connectivity, structural connectivity, diffusion tensor imaging, DTI, MRI, social perception, superior temporal sulcus, temporoparietal junction, anxiety.

Read More
Second-hand stress: inhalation of stress sweat enhances neural response to neutral faces
Social Cognitive and Affective Neuroscience
•
2012

Authors: Rubin, Botanov, Hajcak, Mujica-Parodi. Keywords: chemosensory, chemosignals, stress sweat, sweat, stress, skydive, skydiving, faces, threat, emotion, event-related potentials, ERP, late positive potential, LPP, EEG, attention.

Read More
Power spectrum scale invariance identifies prefrontal dysregulation in paranoid schizophrenia
Human Brain Mapping
•
2011

Authors: Radulescu, Rubin, Strey, Mujica-Parodi. Keywords: schizophrenia, paranoid schizophrenia, power spectrum scale invariance, PSSI, pink noise, white noise, Poincaré maps, complexity, chaos, regulation, dysregulation, prefrontal cortex, orbitofrontal cortex, Brodmann Area 10, prefrontal-limbic, emotion, fMRI, functional magnetic resonance imaging.

Read More
The orienting of spatial attention to backward masked fearful faces is associated with variation in the serotonin transporter gene
Emotion
•
2012

Authors: Carlson, Mujica-Parodi, Harmon-Jones, Hajcak. Keywords: serotonin transporter gene, 5HTTLPR, genetics, genotype, spatial attention, attention bias, orienting, threat, masked fearful faces, fear, backward masking, dot-probe, nonconscious.

Read More
Nonconscious attention bias to threat is correlated with anterior cingulate cortex gray matter volume: a voxel-based morphometry result and replication
NeuroImage
•
2012

Authors: Carlson, Beacher, Reinke, Habib, Harmon-Jones, Mujica-Parodi, Hajcak. Keywords: attention bias, threat, fear, nonconscious, masked fearful faces, backward masking, dot-probe, anterior cingulate cortex, ACC, amygdala, gray matter volume, voxel-based morphometry, VBM, structural MRI, magnetic resonance imaging, anxiety, replication.

Read More
Neural reactivity tracks fear generalization gradients
Biological Psychology
•
2013

Authors: Greenberg, Carlson, Cha, Hajcak, Mujica-Parodi. Keywords: fear generalization, fear conditioning, generalization gradient, conditioned stimulus, insula, anterior cingulate, caudate, supplementary motor area, neural reactivity, pupillary response.

Read More
Trait reappraisal is associated with resilience to acute psychological stress
Journal of Research in Personality
•
2012

Authors: Carlson, Dikecligil, Greenberg, Mujica-Parodi. Keywords: reappraisal, trait reappraisal, resilience, stress, acute psychological stress.

Read More
A stand-alone method for anatomical localization of NIRS measurements
NeuroImage
•
2011

Authors: Fekete, Rubin, Carlson, Mujica-Parodi. Keywords: near-infrared spectroscopy, NIRS, fNIRS, anatomical localization, optodes, registration, algorithm, NIRS Analysis Package, NAP, Matlab toolbox, software, methods.

Read More
The NIRS Analysis Package: noise reduction and statistical inference
PLOS ONE
•
2011

Authors: Fekete, Rubin, Carlson, Mujica-Parodi. Keywords: near-infrared spectroscopy, NIRS, fNIRS, NIRS Analysis Package, NAP, Matlab toolbox, software, noise reduction, motion artifacts, statistical inference, general linear model, hemodynamic, methods.

Read More
Acute stress eliminates female advantage in detection of ambiguous negative affect
Evolutionary Psychology
•
2011

Authors: DeDora, Carlson, Mujica-Parodi. Keywords: stress, acute stress, skydive, skydiving, threat, emotion identification, ambiguous faces, aggression, affect, sex differences, gender, women, virtual reality.

Read More
Feeling anxious: anticipatory amygdalo-insular response predicts the feeling of anxious anticipation
Social Cognitive and Affective Neuroscience
•
2011

Authors: Carlson, Greenberg, Rubin, Mujica-Parodi. Keywords: anxiety, anxious anticipation, anticipation, trait anxiety, anterior insula, insula, amygdala, interoception, fMRI, functional magnetic resonance imaging, aversive.

Read More
Ventral striatal and medial prefrontal BOLD activation is correlated with reward-related electrocortical activity: a combined ERP and fMRI study
NeuroImage
•
2011

Authors: Carlson, Foti, Mujica-Parodi, Harmon-Jones, Hajcak. Keywords: reward, reward processing, ventral striatum, nucleus accumbens, medial prefrontal cortex, mesocorticolimbic, dopamine, feedback negativity, event-related potentials, ERP, EEG, fMRI, functional magnetic resonance imaging, BOLD, gambling task, multimodal.

Read More
Power spectrum scale invariance quantifies limbic dysregulation in trait anxious adults using fMRI: adapting methods optimized for characterizing autonomic dysregulation to neural dynamic time series.
NeuroImage
•
2010

Authors: Tolkunov, Rubin, Mujica-Parodi. Keywords: power spectrum scale invariance, PSSI, power spectrum density, power-law scaling, self-similarity, control system, negative feedback, regulation, dysregulation, limbic, amygdala, trait anxiety, anxiety, heart rate variability, HRV, autonomic, fMRI, functional MRI, time series, faces.

Read More
Ambulatory and challenge-associated heart rate variability measures predict cardiac responses to real-world acute emotional stress.
Biological Psychiatry
•
2010

Authors: Dikecligil, Mujica-Parodi. Keywords: heart rate variability, HRV, ECG, electrocardiogram, Holter, ambulatory, autonomic nervous system, stress, acute emotional stress, skydive, skydiving, cardiac, regulation.

Read More
A disposition to reappraise decreases anterior insula reactivity during anxious anticipation
Biological Psychology
•
2010

Authors: Carlson, Mujica-Parodi. Keywords: reappraisal, dispositional reappraisal, emotion regulation, anxious anticipation, anticipation, anxiety, anterior insula, insula, fMRI, functional magnetic resonance imaging, aversive.

Read More
Blind rage? Heightened anger is associated with altered amygdala responses to masked and unmasked fearful faces
Psychiatry Research
•
2009

Authors: Carlson, Greenberg, Mujica-Parodi. Keywords: anger, trait anger, anger expression, aggression, amygdala, fearful faces, masked faces, fear, BOLD, fMRI.

Read More
Power Spectrum Density and Shannon Entropy Methods Quantify Limbic Dysregulation using fMRI and NIRS.
NeuroImage
•
2009

Authors: Tolkunov, Rubin, Carlson, Greenberg, Mujica-Parodi. Keywords: power spectrum density, Shannon entropy, entropy, limbic, dysregulation, fMRI, NIRS, near-infrared spectroscopy.

Read More
Anger expression and stress responses in military men
Aviation, Space, and Environmental Medicine
•
2009

Authors: Taylor, Mujica-Parodi, Potterat, Momen, Ward, Padilla, Markham, Evans. Keywords: anger, anger expression, stress, stress response, military, survival training, operational stress, individual differences.

Read More
Behavioral predictors of acute stress symptoms during intense military training
Journal of Traumatic Stress
•
2009

Authors: Taylor, Mujica-Parodi, Padilla, Markham, Potterat, Momen, Sander, Larson. Keywords: stress, acute stress, coping, perceived stress, military, survival training, behavioral predictors.

Read More
A principal component network analysis of prefrontal-limbic functional magnetic resonance imaging time series in schizophrenia patients and healthy controls
Psychiatry Research
•
2009

Authors: Rădulescu, Radulescu, Mujica-Parodi. Keywords: schizophrenia, prefrontal-limbic, amygdala, hippocampus, prefrontal cortex, principal component analysis, PCA, network analysis, time series, emotional arousal, emotion, faces, fMRI, functional magnetic resonance imaging, dysregulation, dynamics.

Read More
Chemosensory cues to conspecific emotional stress activate amygdala in humans.
PLOS ONE
•
2009

Authors: Mujica-Parodi, Strey, Frederick, Savoy, Cox, Botanov, Tolkunov, Rubin, Weber. Keywords: chemosensory, chemosignals, alarm substances, stress sweat, sweat, emotional stress, stress, amygdala, olfaction, odor, emotion perception, fMRI.

Read More
Higher body fat percentage is associated with increased cortisol reactivity and impaired cognitive resilience in response to acute emotional stress
International Journal of Obesity
•
2009

Authors: Mujica-Parodi, Renelique, Taylor. Keywords: body fat, cortisol, endocrine, stress, acute emotional stress, skydive, skydiving, cognition, cognitive resilience, working memory, spatial processing, attention, heart rate variability, HRV, autonomic, anxiety.

Read More
Limbic dysregulation is associated with lowered heart rate variability and increased trait anxiety in healthy adults
Human Brain Mapping
•
2009

Authors: Mujica-Parodi, Korgaonkar, Ravindranath, Greenberg, Tomasi, Wagshul, Ardekani, Guilfoyle, Khan, Zhong, Chon, Malaspina. Keywords: limbic, dysregulation, regulation, control system, negative feedback, heart rate variability, HRV, ECG, autonomic, sympathetic, trait anxiety, anxiety, amygdala, hippocampus, prefrontal, faces, fMRI, BOLD, time series.

Read More
Physical fitness influences stress reactions to extreme military training
Military Medicine
•
2008

Authors: Taylor, Markham, Reis, Padilla, Potterat, Drummond, Mujica-Parodi. Keywords: physical fitness, aerobic fitness, stress, military, survival training, trait anxiety, post-traumatic stress disorder, PTSD, Impact of Events Scale.

Read More
A systems approach to prefrontal-limbic dysregulation in schizophrenia
Neuropsychobiology
•
2008

Authors: Rădulescu, Radulescu, Mujica-Parodi. Keywords: schizophrenia, prefrontal-limbic, dysregulation, control systems, systems approach, negative feedback, homeostasis, perturbation, amygdala, prefrontal cortex, Brodmann area 9, emotional arousal, faces, fMRI, functional magnetic resonance imaging, time series, cross-correlation.

Read More
Stressful military training: endocrine reactivity, performance, and psychological impact
Aviation, Space, and Environmental Medicine
•
2007

Authors: Taylor, Sausen, Potterat, Mujica-Parodi, Reis, Markham, Padilla, Taylor. Keywords: stress, military, survival training, cortisol, DHEAS, dehydroepiandrosterone, endocrine, allostatic load, performance, dissociation, PTSD.

Read More
Neurophysiologic methods to measure stress during survival, evasion, resistance, and escape training
Aviation, Space, and Environmental Medicine
•
2007

Authors: Taylor, Sausen, Mujica-Parodi, Potterat, Yanagi, Kim. Keywords: stress, operational stress, military, SERE, survival training, neurophysiology, neuroendocrine, fMRI, acoustic startle, heart rate variability, HRV, cardiac, performance, systems approach, methods.

Read More
Nonlinear complexity and spectral analyses of heart rate variability in medicated and unmedicated patients with schizophrenia
Neuropsychobiology
•
2005

Authors: Mujica-Parodi, Yeragani, Malaspina. Keywords: schizophrenia, psychosis, heart rate variability, HRV, ECG, autonomic nervous system, vagal, cardiac, nonlinear complexity, symbolic dynamics, spectral analysis, atypical antipsychotics, medication, stress, sleep, limbic.

Read More
The reliability and clinical correlates of figure-ground perception in schizophrenia
Neuropsychology
•
2004

Authors: Malaspina, Simon, Goetz, Corcoran, Coleman, Printz, Mujica-Parodi, Wolitzky. Keywords: schizophrenia, figure-ground perception, visual perception, visual attention, neuropsychology, negative symptoms, reliability, top-down processing.

Read More
Resting neural activity distinguishes subgroups of schizophrenia patients
Biological Psychiatry
•
2004

Authors: Malaspina, Harkavy-Friedman, Corcoran, Mujica-Parodi, Printz, Gorman, Van Heertum. Keywords: schizophrenia, familial, sporadic, subgroups, heterogeneity, resting, regional cerebral blood flow, rCBF, SPECT, single photon emission computed tomography, hypofrontality, neuroimaging.

Read More
Are cognitive symptoms of schizophrenia mediated by abnormalities in emotional arousal?
CNS Spectrums
•
2002

Authors: Mujica-Parodi, Corcoran, Greenberg, Sackeim, Malaspina. Keywords: schizophrenia, delusions, formal thought disorder, cognitive symptoms, logical reasoning, cognitive gating, emotional arousal, arousal, affect, stress, information processing, jumping to conclusions.

Read More
Could stress cause psychosis in individuals vulnerable to schizophrenia?
CNS Spectrums
•
2002

Authors: Corcoran, Mujica-Parodi, Yale, Leitman, Malaspina. Keywords: schizophrenia, psychosis, stress, psychosocial stress, vulnerability, hippocampus, neurotoxicity, neurodevelopmental model, neurodegeneration, gene-environment interaction, MRI.

Read More
Logical processing, affect, and delusional thought in schizophrenia
Harvard Review of Psychiatry
•
2000

Authors: Mujica-Parodi, Malaspina, Sackeim. Keywords: schizophrenia, delusions, delusional thought, logical reasoning, logic, logical processing, affect, emotion, inference, premises.

Read More